Staph Lab

Therapeutic Development

Targeting quorum sensing for anti-virulence therapy

Our interest in bacterial quorum sensing lead to efforts to target this regulatory pathway for development of anti-virulence therapies. Through collaborative efforts with several laboratories, we helped identify a couple new compounds that inhibit S. aureus quorum sensing and infection development by targeting the AgrA DNA binding protein. We currently are investigating the mechanisms of new leads.

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Horswill Laboratory, University of Colorado.

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Lab Info
Research Complex 1 North
12800 E. 19th Ave., Rm. P18-9101

Alexandar Horswill, PhD
Professor of Immunology and Microbiology

(303) 724-4224