Alexander Horswill Laboratory
A. Horswill Laboratory


Research in the Horswill laboratory is focused on the bacterial pathogen Staphylococcus aureus. We are interested in the function of the peptide quorum-sensing system and other signal transduction systems in regulating virulence factor production, and the roles of these systems in biofilm formation and host-pathogen interactions.

Recent Papers

Sommerfeld Ross S, Tu MH, Falsetta ML, Ketterer MR, Kiedrowski MR, Horswill AR, Apicella MA, Reinhardt JM, Fiegel J. Quantification of confocal images of biofilms grown on irregular surfaces. J. Microbiol. Methods 2014 100(), 111-20
Pang YY, Schwartz J, Bloomberg S, Boyd JM, Horswill AR, Nauseef WM. Methionine Sulfoxide Reductases Protect against Oxidative Stress in Staphylococcus aureus Encountering Exogenous Oxidants and Human Neutrophils. J Innate Immun 2014 6(3), 353-64
White MJ, Boyd JM, Horswill AR, Nauseef WM. Phosphatidylinositol-Specific Phospholipase C Contributes to Survival of Staphylococcus aureus USA300 in Human Blood and Neutrophils. Infect. Immun. 2014 82(4), 1559-71

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