A. Horswill Laboratory

Welcome

Research in the Horswill laboratory is focused on the bacterial pathogen Staphylococcus aureus. We are interested in the function of the peptide quorum-sensing system and other signal transduction systems in regulating virulence factor production, and the roles of these systems in biofilm formation and host-pathogen interactions.

Recent Papers

Nygaard TK, Pallister KB, Dumont AL, Dewald M, Watkins RL, Pallister EQ, Malone C, Griffith S, Horswill AR, Torres VJ, Voyich JM. Alpha-Toxin Induces Programmed Cell Death of Human T cells, B cells, and Monocytes during USA300 Infection. PLoS ONE 2012 7(5), e36532

Gonzalez DJ, Okumura CY, Hollands A, Kersten R, Akong-Moore K, Pence MA, Malone CL, Derieux J, Moore BS, Horswill AR, Dixon JE, Dorrestein PC, Nizet V. Novel Phenol-soluble Modulin Derivatives in Community-associated Methicillin-resistant Staphylococcus aureus Identified through Imaging Mass Spectrometry. J. Biol. Chem. 2012 287(17), 13889-98

Hernandez FJ, Stockdale KR, Huang L, Horswill AR, Behlke MA, McNamara JO. Degradation of nuclease-stabilized RNA oligonucleotides in Mycoplasma-contaminated cell culture media. Nucleic Acid Ther 2012 22(1), 58-68

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