Alex Horswill PhD
Research in the Horswill laboratory is focused on the bacterial pathogen Staphylococcus aureus
. We are interested in the function of the peptide quorum-sensing system and other signal transduction systems in regulating virulence factor production, and the roles of these systems in biofilm formation and host-pathogen interactions.Recent efforts have suggested that S. aureus quorum sensing and biofilm formation are interconnected. The ability of S. aureus to develop biofilms on medical implants is an important determinant in infections, high-lighting the need for more studies in this area. As we learn more about AIP biosynthesis and regulation, this research will be extended toward studies on biofilms, with a goal of improving our understanding of this connection.
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